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Case Series
The use of bioactive glass as a posterolateral graft in patients with infected spondylodesis
1 Doctor of Medicine, MD, Orthopedics, Maastricht University Medical Centre, Maastricht, The Netherlands
2 Orthopedic Surgeon, MD, PhD, Orthopedics, Maastricht University Medical Centre, Maastricht, The Netherlands
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Paulien van de Voorde
Postbus 5800, 6202 AZ Maastricht,
The Netherlands
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Article ID: 100019Z14PV2019
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van de Voorde P, Geurts JAP. The use of bioactive glass as a posterolateral graft in patients with infected spondylodesis. J Case Rep Images Orthop Rheum 2019;4:100019Z14PV2019.ABSTRACT
Introduction: Bioactive glass is used increasingly, also as a bone graft in spondylodesis. Autologous bone is used for the pursuit of a solid spinal fusion in spondylodesis. Iliac crest bone is most commonly used as a donor site for obtaining autologous bone graft. The use of autologous bone is associated with some risks and higher comorbidity. For these reasons, surrogates are used. In the case of infected spondylodesis material, in contrast to infection treatment with arthroplasty, the material remains in situ to maintain stabilization. In such cases, only the autologous bone grafts are removed. Therefore, a substitution material will have to be put back that generates fusion and offers treatment to the underlying infection. Bioactive glass could potentially make an important contribution to this.
Case Series: In this case series, we want to provide an initial insight into the use of bioactive glass, used in a combined setting, in patients with infected spondylodesis material. We present four cases of different patients.
Conclusion: In all cases, there were no signs of persisting infection and it was confirmed that the use of bioactive glass also maintains the spinal fusion.
Keywords: Bioactive glass, Infection, Spondylodesis
SUPPORTING INFORMATION
Author Contributions
Paulien van de Voorde - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jan AP Geurts - Substantial contributions to conception and design, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestSenior author is member of the BonAlive Clinical Advisory Board.
Copyright© 2019 Paulien van de Voorde et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
